Batch 001 - Live Allocation
Q4 launch pricing · ends 31 Dec
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◇ Compound Reference

GROWTH HORMONE SUPPORTInvestigationalPopular

CJC-1295 (No DAC)

GHRH Analog · 10mg

Vial size
Status
Investigational
Route
SubQ
Half-life
~30 minutes plasma
Class
GHRH analog
MechanismGHRH Receptor Agonism
Cohort92 active prescriptions
Educational reference only - not a prescription or dosing recommendation. Some compounds are investigational or used off-label; suitability is a question for your own doctor. See Informed Consent & Disclaimer.
V-Series Member
$55.58 USD/vial
À-la-carte: $58.50 USD/vial · Save 5%
Q4 launch pricing until 31 Dec · regular $65 USD/vial from 1 Jan
Vials per allocation
Member total (1×)$55.58
À-la-carte total$58.50
Flat per-vial pricing. International shipping $35, free on orders of $250 or more.
What this is

Modified GHRH analog with optimized pharmacokinetics. Paired with ghrelin mimetics for synergistic GH pulse amplification.

GHRH Analog · 10mg per vial · lot-tested.

◇
Janoshik Verified
HPLC + MS purity, every batch
Independent third-party lab
⬡
COA Per Batch
Lot-level certificates published
Labeled vs actual mg disclosed
⊙
Lot-Tested
Every lot, independent lab
Report and verification code per lot
CJC-1295 (No DAC) · Growth hormone support
◆ Certificate of Analysis · CJC-1295 (No DAC)
JANOSHIK ANALYTICALHPLC + MS · Independent third-party
Batch 001 · lot VL-CJC-2026-07A

Every 100 units are drawn from one lot and tested once. The certificate below is the one that applies to this batch - when it closes, the next opens with a new lot and a new certificate.

Lot testing in progress. The independent lab report for this CJC-1295 (No DAC) lot will be published here, with its verification code, as soon as it is back.
◉
Clinical Overview
CJC-1295 (No DAC)

CJC-1295 (without DAC) is a tetrasubstituted GHRH analog. The "without DAC" designation indicates no Drug Affinity Complex, resulting in a shorter half-life that better mimics the natural pulsatile GH release pattern.

The version "with DAC" has a much longer half-life and is generally avoided in modern practice.

✦
GHRH Agonism
Stabilized GHRH analog amplifying GH pulses.
❖
Synergistic Pairing
Typically paired with a GHRP (e.g. Ipamorelin) for synergy.
◈
GH-Axis Support
Supports endogenous growth-hormone secretion.
◈
Mechanism
How It Works

GHRH receptor agonism with enhanced stability vs. native GHRH due to amino acid modifications. Typically paired with a GHRP (Ipamorelin or GHRP-2) for synergistic GH pulse amplification.

✚
Patient Bloodwork Guide
Bloodwork for Growth-Hormone Protocols

GHRH / GHRP secretagogues - Tesamorelin, CJC-1295, Ipamorelin, V-G1

These protocols gently restore your body’s own pulsing release of growth hormone rather than replacing it. Because growth hormone also affects blood sugar, monitoring confirms two things: that it is working, and that it is doing so safely.

Incremental approach. Vivre starts below the standard dose and advances only on tolerance. This monitoring is the safety scaffold for that conservative approach.

Is it working? (Efficacy)
IGF-1The main signal of your overall growth-hormone output across the day.
IGFBP-3The protein that carries IGF-1 - measured alongside it for a clearer picture of how much is active.
Blood sugar & metabolism (watch closely)
Fasting insulinThe earliest warning sign of insulin resistance - it moves before blood sugar does.
HbA1cYour average blood sugar over ~3 months. Especially relevant with Tesamorelin.
Fasting glucoseA routine blood-sugar check.
Keeping side effects in check
ProlactinIpamorelin (the one Vivre uses) is highly selective and rarely affects this; checked as good practice.
Cortisol (AM)A stress-hormone check included for completeness.
Overall safety
hs-CRPA sensitive inflammation marker - confirms recovery, not strain.
CBC & CMPStandard blood count, liver, and kidney panels.
When the tests happen
Baseline (before you start)Full panel - your natural starting point.
Mid-cycle (week 6–8)IGF-1, fasting insulin, prolactin/cortisol - confirm it works, catch sugar drift early.
Post-cycle (4 weeks off)IGF-1 and fasting insulin - confirm natural production recovers.

Educational only - not medical advice or a dosing instruction. Your own doctor orders tests, interprets results and decides what is right for you. See the Informed Consent & Disclaimer for full terms.

⊞
Technical Profile
Measurable Properties
ClassGHRH analogue (no DAC variant)
MechanismGHRH-receptor agonism; stimulates endogenous GH pulsatility
Terminal half-lifeNo-DAC variant short-acting (~30 min order); DAC variant substantially longer
MetabolismPeptidase degradation
Evidence baseModerate; limited large controlled human trials
Regulatory statusNot an approved therapy; research use only
Certificate of Analysis (per batch)
Analytical method: UHPLC-MS. Batch COA available on request - link to be populated per shipment.
COA link - pending per batch
PK differs markedly between DAC/no-DAC forms. Educational only; not a dosing instruction.
§
Clinical Literature
Peer-Reviewed References

Prolonged Stimulation of GH and IGF-I Secretion by CJC-1295, a Long-Acting Analog of GHRH, in Healthy Adults

Teichman SL, Neale A, Lawrence B, Gagnon C, Castaigne JP, Frohman LA · 2006 · Journal of Clinical Endocrinology & Metabolism 2006;91(3):799–805
▾

Findings

Two randomized, placebo-controlled, double-blind ascending-dose trials in healthy adults aged 21–61 (DOI 10.1210/jc.2005-1536). A single subcutaneous injection produced dose-dependent increases in mean plasma GH (2–10× for ≥6 days) and IGF-I (1.5–3× for 9–11 days); estimated half-life 5.8–8.1 days. After multiple doses, mean IGF-I stayed above baseline up to 28 days, with evidence of cumulative effect. No serious adverse reactions; well tolerated at 30–60 μg/kg. CRITICAL FRAMING: the studied agent was the DAC-modified long-acting variant, which produces SUSTAINED (continuous) GH/IGF-I elevation. Vivre uses the No-DAC (Mod GRF 1-29) form, which has a ~30-minute half-life and produces PULSATILE GH release that better mimics physiology. This study supports the GH-axis mechanism but does not endorse continuous-elevation (DAC) dosing for longevity use.

View on publisher ↗
CJC-1295 pharmacology is reasonably well-characterised across both DAC and No-DAC variants; the Teichman 2006 human data is for the DAC form. Vivre uses only the No-DAC variant - for its pulsatile (rather than sustained) GH-release profile. The distinction matters clinically: the DAC form binds albumin (~7–8 day half-life) and drives a continuous "GH bleed" - 24/7 GH/IGF-I elevation with no rest window - which raises the theoretical concerns around insulin resistance and chronic IGF-1 exposure (see the GH/IGF-1 safety reference). Many longevity physicians avoid the DAC form for exactly this reason. The No-DAC form's brief (~30 min) pulses return to baseline between doses, more closely mimicking youthful physiologic secretion. CJC-1295 is on the WADA Prohibited List as a GH secretagogue.
◇
Clinical Applications
Indications
  • GH optimization protocols
  • Body composition support
  • Recovery and sleep support
  • Component of GH-secretagogue stacks
⊙
Pharmacokinetics
Half-Life & Duration of Action
Half-life is how long a compound stays at active plasma concentration in your body. Most peptides in this catalogue have short plasma half-lives - they clear from your bloodstream within hours, sometimes minutes. The long-half-life compounds in this catalogue are the approved-class incretins (Tirzepatide, Semaglutide, Retatrutide), which are designed for once-weekly dosing - that's the molecular engineering choice that makes weekly dosing work.
Plasma Half-Life
~30 minutes plasma (CJC-1295 without DAC; multiple published sources). Produces a clean discrete GH pulse via GHRH-receptor activation. The DAC-modified version, NOT offered at Vivre, has a much longer half-life (~6-8 days) but is associated with sustained rather than pulsatile GH elevation.
Why this matters for you
If you don't tolerate a compound or need to discontinue a protocol, short-half-life peptides are out of your bloodstream within hours - not days or weeks. That said, the biological effects they initiate (tissue repair signalling, mitochondrial signalling, gene expression changes) often persist longer than the peptide itself, through downstream cellular cascades. This is normal peptide pharmacology and is important context - the molecule clears fast, but the biology takes longer to wind down.
Evidence Base
Limited human clinical trials. Widespread use in compounding pharmacy practice.
Dosing protocols, administration frequency, and titration schedules are not published on these public pages.
◎
Commonly Paired
Compounds Often Paired With CJC-1295 (No DAC)
Clinical co-allocation patterns observed in Vivre's allocation history. Pairings are not prescriptions.
GHRP
Ipamorelin
Ghrelin Mimetic · 10mg
◆ GH-axis stack
CJC-1295 (No DAC) paired with Ipamorelin amplifies pulsatile GH release through complementary, non-competing pathways. This pairing IS Vivre's V-G1 protocol - pre-blended into a single vial (Jodomi JD-C104).
View Ipamorelin detail →
FOR CUSTOMERS

Mixing guide and dosage calculator

Unlocks once you order CJC-1295 (No DAC): step-by-step mixing with illustrations, storage, and a calculator that converts any dose to syringe units at your vial strength.

READY TO PROCEED

Start with the Biological Audit

CJC-1295 (No DAC) is verified and lot-tested, dispensed following a Biological Audit. The Audit is complimentary for the Batch 001 cohort.

$55.58 USD/vial
CJC-1295 (No DAC) · Member rate
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Products are sold for research use only and are not intended to diagnose, treat, cure or prevent any disease. Content on this site is educational and is not medical advice. Lot results apply to the lot tested; see each report for details. For adults 21 and over.

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